Development and Validation of Uv Spectrophotometric Estimation of Perindopril Erbumine and Indapamide in Bulk and Tablet Dosage by Using Area Under Curve Method
Keywords:
validation, perindopril erbumine, indapamide, uv visible spectrophotometry, auc methodAbstract
A simple, precise, accurate, and economical UV visible spectrophotometric method has been developed for estimation of Perindopril erbumine & Indapamide drug by AUC method. Quantitative determination of the drug was performed at wavelength range 208-214 nm and 239-244 nm for Perindopril erbumine & Indapamide respectively. The linearity was established over the concentration range of 10-50 µg/ml for Perindopril erbumine and 1-5 µg/ml for Indapamide with correlation coefficient value of 0.999 for both the drugs. Precision studies showed that % relative standard deviation was within range of acceptable limits. The recovery study was found to be within range of 99-101%. The proposed method has been validated as per ICH guidelines.
References
Darshana K. Modi, Chhagan N. Patel (2010) Development and Validation of Spectrophotometric Method for Simultaneous Estimation of Perindopril and Indapamide in Combined Dosage Form by Absorbance Correction Method. 2(1), 411-416.
Chaudhary AB, Patel RK, Chaudhari SA (2010) Determination of Losartan Potassium and Perindopril Erbumine in Tablet Formulations by Reversed-Phase HPLC. 2(2), 1141-6.
Pawar PV, Gaikwad PD, Bankar VH, Pawar SP (2010) Development and validation of UV-spectrophotometric method for simultaneous estimation of Atenolol and Indapamide in bulk and tablet dosage form. 2(4), 876-85.
Shweta Bhadani, Mohan Sellappan (2013) Development and Validation of RP-HPLC Method for Simultaneous Estimation of Perindopril Erbumine and Indapamide in Combined Dosage Form. 3(3), 704-711.
Raveendra Babu Ganduri, Durga Mallikarjuna Rao Tippa, Jayachandra Reddy Peddapapireddigari, Himabindu Vurimindi (2014) Stability indicating liquid chromatographic method for the determination of related substances of Perindopril Erbumine and Indapamide from combined tablet dosage form. 02(4), 255-266.
A.H. Bekett, J.B. Stenlake (2002) Practical Pharmaceutical Chemistry. 275-337.
Shankar R.S. Dr. (1997) Text book of Pharmaceutical Analysis. 1.17-1.18.
A.V. Dr. Kasture, K.R. Dr. Mahadik, S.G. Dr. Wadodkar, H.N. Dr. More (2005) Text book of Pharmaceutical Analysis Instrumental Methods. 2, 174.
(2005) Validation of analytical procedure: text and methodology. 1-3.
(2005) Validation of Analytical Procedure: Methodology.
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