Chemical Diversity of Propolis from Meliponinae: An Ancestral Treasure to be Preserved
Keywords:
HEA coating; DGPSAT; aging treatment; hardness; tribology propertiesAbstract
Propolis is a mixture made by bees consisting of plant resins and metabolites, salivary enzymes and wax. Some species of bees add soil to this mixture forming geopropolis. This material is used in the defense of the hive as a physical barrier and antimicrobial agent, ensuring the health of the colony. Propolis has been extensively studied and several chemical constituents have been identified, mainly flavonoids, terpenes and phenolics. With the emerging microbial resistance to antibiotics, the interest in the search for active compounds, mainly secondary metabolites of plants, has been increasing significantly. In this paper, we describe the characteristics of the main species of native stingless bees found in South America, especially in Brazil, the ancestral use of propolis produced by them, its chemical composition and its potential for the development of new therapeutic compounds, along with the challenges that the survival of bees face.
References
A. C. Abreu, A. J. McBain, M. Simões (2012) Plants as sources of new antimicrobials and resistance-modifying agents. 29(9), 1007-1021.
M. J. A. M. Araújo, et al (2015) The chemical composition and pharmacological activities of geopropolis produced by Melipona fasciculata Smith in Northeast Brazil. 4(1), 12-20.
S. Athayde, et al (2016) Engaging indigenous and academic knowledge on bees in the Amazon: implications for environmental management and transdisciplinary research. 12(1).
R. Ayala, et al (2013) Mexican Stingless Bees (Hymenoptera: Apidae): Diversity, Distribution, and Indigenous Knowledge. 135-152.
F. Bakkali, et al (2008) Biological effects of essential oils – A review. 46(2), 446-475.
J. M. P. P. Ballivián, et al (org.) (2008) Native stingless bees: Myg pe.. 128.
V. Bankova, S. Castro, M. Marcucci (1998) Constituents of Brazilian Geopropolis. 53(5-6), 402-406.
V. Bankova, S. Castro, M. Marcucci (1999) Phytochemical Evidence for the Plant Origin of Brazilian Propolis from São Paulo State. 401-405.
V. Bankova, S. Castro, M. Marcucci (2000) Propolis: recent advances in chemistry and plant origin. 31(1), 3-15.
V. Bankova, M. Popova, B. Trusheva (2014) Propolis volatile compounds: Chemical diversity and biological activity: A review. 8(1), 1 – 8.
M. C. A. Batista, et al (2016) Chemical composition and antioxidant activity of geopropolis produced by Melipona fasciculata (Meliponinae) in flooded fields and cerrado areas of Maranhão State, northeastern Brazil. 46(3), 315-322.
J. S. Bonsucesso, et al (2018) Metals in geopropolis from beehive of Melipona scutellaris in urban environments. 634, 687-694.
H. F. E. Breyer, E. D. H. Breyer, I. Cella (2016) Production and processing of propolis. 21.
B. Caballero, L. C. Trugo, P. M. Finglas (2003) Encyclopedia of Food Sciences and Nutrition, 2nd ed..
S. Castaldo, F. Capasso (2002) Propolis, an old remedy used in modern medicine. 73.
E. Crane (1999) The World History of Beekeeping and Honey Hunting. 720 p..
A. S. Dorigo, et al. (2019) In vitro larval rearing protocol for the stingless bee species Melipona scutellaris for toxicological studies. 14(3).
V. S. Dubey, R. Bhallia, R. Luthra (2003) An overview of the non-mevalonate pathway for terpenoid biosynthesis in plants. 637–646.
R. P. Dutra, et al. (2014) Phenolic Acids, Hydrolyzable Tannins, and Antioxidant Activity of Geopropolis from the Stingless Bee Melipona fasciculata Smith. 62, 2549-2557.
F. H. Fernandes, et al. (2015) Evaluation of mutagenic and antimicrobial properties of brown propolis essential oil from the Brazilian Cerrado biome. 2, 1482–1488.
V. L. I. Fonseca, (ed.) (2017) The bee had jandaíra: in the past, present and in the future. 254 p..
M. Hrncir, et al. (2016) Stingless bees (Meliponini): senses and behavior. 202(9-10), 597-601.
W. E. Kerr (2002) Extinction of species: the great biological crisis of the moment and how it affects the meliponines. 4 – 9.
A. M. P. Kleinert, et al. (2009) Social bees: Bombini, Apini, Meliponini. 373-426.
A. Kujumgiev, I. Tsvetkova, Y. Serkedjieva, et al. (1999) Antibacterial, antifungal and antiviral activity of propolis of different geographic origin. 64, 235-40.
F. C. Lavinas, et al. (2019) Brazilian stingless bee propolis and geopropolis: promising sources of biologically active compounds. 29(3), 389-399.
H. Lexikon (1997) Dictionary of symbols. 214 p..
S. A. Liberio, et al. (2011) Antimicrobial activity against oral pathogens and immunomodulatory effects and toxicity of geopropolis produced by the stingless bee Melipona fasciculata Smith. 11(108).
M. C. Marcucci (1996) Biological and therapeutic properties of the chemical constituents of propolis. 19(5), 529-536.
E. Melliou, E. Stratis, I. Chinou (2007) Volatile constituents of propolis from various regions of Greece – Antimicrobial activity. 103(1), 375-380.
H. Menezes (2005) Propolis: a review of recent studies of its pharmacological properties. 72(3), 405-411.
C. D. Michener (2000) The bees of the world. 913.
F. Müller (1874) The habits of various insects. 10, 102-103.
D. J. Newman, G. M. Cragg (2020) Natural Products as Sources of New Drugs over the Nearly four Decades from 01/1981 to 09/2019. 83(3), 770-803.
P. Nogueira-Neto (1997) Life and Breeding of Stingless Indigenous Bees. 445.
A. P. Oliveira, et al. et al. (2009) Chemical composition and antibacterial activity of Brazilian propolis essential oil. 16(1), 121-130.
F. F. de Oliveira, et al. et al. (2013) Illustrated Guide to the 'Stingless' Bees of the Amanã and Mamirauá Reserves, Amazonas, Brazil: (hymenoptera, apidae, meliponini). 267.
A. D. S. Pereira, F. R. M. S. Seixas, F. R. D. A. Neto (2002) Propolis: 100 years of research and its future prospects. 25, 321-326.
A. S. Portal, S. Schiqet, A. M. Padilha Amaral, K. Mascarenhas Krepsky, L. Curbani, R. Andrade Rebeiro, M. Rau, S. L. Althoff, A. Guedes, C. M. Mendes de Cordova (2023) Composition, Antibiofilm, and Antibacterial Potential of Volatile Oils from Geopropolis of Different Stingless Bees' Species. https://doi.org/10.1002/cbdv.202300592
A. D. S. Rodrigues (2005) Ethnoknowledge about stingless bees: knowledge and practices of the M-byá Guarani Indians in the Atlantic forest. 253.
L. C. Rufatto, et al. et al. (2017) Red propolis: Chemical composition and pharmacological activity. 7(7), 591-598.
A Salatino, et al. (2005) Origin and Chemical Variation of Brazilian Propolis. 2(1), 33-38.
H F D Santos, et al. (2017) Chemical Profile and Antioxidant, Anti-Inflammatory, Antimutagenic and Antimicrobial Activities of Geopropolis from the Stingless Bee Melipona orbignyi. 18(5), 953-970.
J M Sforcin, et al. (2017) Propolis and Geopropolis: a bee inheritance.
C I Silva, et al. (2014) Illustrated guide to pollinating bees in Brazil.
E C C D Smith, M P Muniz, R D C S Nunomura (2013) Phenolic constituents and antioxidant activity of geopropolis of two species of Amazonian stingless bees. 36(5), 628-633.
F A Silveira, et al. (2002) Brazilian bees: systematics and identification. 253.
E Simionatto, et al. (2012) Chiral analysis of monoterpenes in volatile oils from propolis. 57, 1240–1243.
M Simoes, R N Bennett, E A S Rosa (2009) Understanding antimicrobial activities of phytochemicals against multidrug resistant bacteria and biofilms. 26(6), 746-757.
R N S Torres, et al. (2008) Volatile constituents of Piauiense propolis. 31, 479–485.
C A Triplehorn, N F Johnson (2005) Borror and De Long's Introduction to the study of insects. 864.
C P Valcanaia, Jbb Masote, Hf Sommer, S Schiquet, B Padilha, L Krepsky, Cj Paganelli, Pp Borges, Lj Danielli, Ma Apel, Kd Soares, S Althoff, Md Alberton, Tkr Botelho, A Guedes, Cm Mendes de Cordova (2022) Antimicrobial Activity of Volatile Oils from Brazilian Stingless Bees Melipona quadrifasciata quadrifasciata and Tetragonisca angustula Propolis. https://doi.org/10.1002/cbdv.202200369
M Velikova, et al. (2000) Chemical composition and biological activity of propolis from Brazilian meliponinae. 55, 785-789.
G C Venturieri (2008) Creation of Indigenous Stingless Bees. 60.
C Viegas Junior, V S Bolzani, E J Barreiro (2006) Natural products and modern medicinal chemistry. 29(2), 326-337.
J VILLAS-BÔAS (2018) Technological Manual: full use of stingless bee products. 212 p..
J VILLAS-BÔAS (2012) Technological Manual: honey from stingless bees. 96 p..
Information network on Brazilian biodiversity in bees. http://www.webbee.org.br/projetos/beelife/mmargin.htm
(2015) Global action plan on antimicrobial resistance. https://apps.who.int/iris/bitstream/10665/193736/9789241509763_eng.pdf?sequence=1
(2017) Prioritization of pathogens to guide discovery, research and development of new antibiotics for drug-resistant bacterial infections, including tuberculosis. https://www.who.int/medicines/areas/rational_use/PPLreport_2017_09_19.pdf?ua=1
A YU, et al. (2016) Patient Safety 2030. https://www.imperial.ac.uk/media/imperial-college/institute-of-global-health-innovation/centre-for-health-policy/Patient-Safety-2030-Report-VFinal.pdf
R A YUNES, V CECHINEL FILHO (2016) Natural Product Chemistry: New Drugs and Modern Pharmacognosy. 528 p..
Downloads
Published
Issue
Section
License
Copyright (c) 2024 Authors and Global Journals Private Limited
This work is licensed under a Creative Commons Attribution 4.0 International License.
